Respiratory Functions, Thoracoabdominal Movements and Exercise Capacity in Neuromuscular Diseases
Brief Summary
The clinical trial titled "Investigation of Respiratory Functions, Thoracoabdominal Movements, and Exercise Capacity in Neuromuscular Diseases" aims to evaluate the respiratory functions, thoracoabdominal movements, and exercise capacity in children with Duchenne Muscular Dystrophy (DMD) and Spinal Muscular Atrophy (SMA) compared to healthy controls. The study will use spirometry, structured light plethysmography (SLP), the six-minute walk test, and the six-minute pegboard ring test to assess these functions. This trial will be conducted at the Lokman Hekim University Muscle and Nerve Diseases Application and Research Center from May 2024 to Dec 2025.
Key Information
Inclusion Criteria:
-
Duchenne Muscular Dystrophy (DMD)
-: Clinically diagnosed with Duchenne Muscular Dystrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study.
Exclusion Criteria:
. Advanced heart failure. 2. Spinal Muscular Atrophy (SMA)
-: Clinically diagnosed with Spinal Muscular Atrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study.
-Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure. 3. Healthy Controls
- Inclusion Criteria:
No diagnosis of neuromuscular diseases. Age above 5 years. Able to breathe independently. Willing to participate in the study.
-Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure.